Reviews and highlights

Elena Real, C.A., P. Mier, N. Sibille, M.A. Andrade-Navarro and P. Bernadó. 2023. The structure-function relationship in protein homorepeats. Curr. Op. Struct. Biol. 83, 102726.

We review recent computational and experimental studies on the structural aspects of protein homorepeats, emphasizing their significance for functional characterization of these low complexity regions.

Schumbera, E., Mier, P. and M.A. Andrade-Navarro. 2023. Phase separating Rho: a widespread regulatory function of disordered regions in proteins revealed in bacteria. Signal Transduct. Target. Ther. 8, 253.

We highlight a paper [Krypotou et al. Science 2023 379(6637):1149-1156] that reports the involvement of an intrinsically disordered region in the bacterial Rho protein in functionally relevant phase separation.

Krolevets, M., V. ten Cate, J.H. Prochaska, A. Schulz, S. Rapp, S. Tenzer, M.A. Andrade-Navarro, S. Horvath, C. Niehrs and P.S. Wild. 2023. DNA methylation and cardiovascular disease in humans: a systematic review and database of known CpG methylation sites. Clin. Epigenetics. 15, 56.

A review of studies reporting differential DNA methylation (CpG sites) in human cardiovascular disease, including a database of 74,580 sites from a total of 99 studies.

Koch, I., M. Andrade-Navarro, M. Schulz and K. Zarnack. 2021. Bioinformatics in Theory and Application – highlights of the 36th German Conference on Bioinformatics. Biol Chem. 402, 869-870

Introduction to a special issue containing papers associated to a conference.

Andrade-Navarro, M.A. 2012. Mining the literature: new methods to exploit keyword profiles. [Research highlight]. Genome Medicine. 8, 41.

Highlight of two papers from Cheung et al. that present a way to build profiles from MeSH terms in sets of MEDLINE abstracts and how to use those profiles to associate genes to diseases, respectively.

Andrade-Navarro, M.A. 2009. The dictionary of genomics, transcriptomics and proteomics. [Book review]. Bioessays31, 1367-1369.

A review of "The dictionary of genomics, transcriptomics and proteomics" by Prof. Günter Kahl and published by Wiley-Blackwell. The book contains 12,000 terms in three volumes and +1800 pages, with the appropriate descriptive level, good illustrations, and opinions on term usage.

Andrade, M.A. 2001. Tools for automated protein annotation. In Protein Sequence Analysis in the Genomic Era. R. Casadio and L. Masotti (Eds.) Clueb, Bologna, Italy.

Three approaches to the problem of automatic protein function annotation.

Andrade, M.A. and C. Sander. 1997. Bioinformatics: from genome data to biological knowledge. Current Opinion in Biotechnology. 8, 675-683.

We reviewed the developments of the year '97 in Bioinformatics Methods from gene detection, and protein sequence analysis, to proteomics. Emphasis was done in pointing to web services where those methods coukd be used, and stored biological information could be accessed.


Faculty Opinions recommendations

Andrade, M. 2021. Faculty Opinions Recommendation of [Nakanishi M et al., Cell 2019 177(4):910-924.e22]. In Faculty Opinions, 08 Jul 2021; 10.3410/f.735530268.793586598

Andrade, M. 2020. Faculty Opinions Recommendation of [Babu MM, Biochem Soc Trans 2016 44(5):1185-1200]. In Faculty Opinions, 03 Mar 2020; 10.3410/f.727061031.793571694