5.-Protein structure -central dogma of Molecular Biology -amino acids, polypeptides -chemical properties of the amino acids, classification -protein structure (different chemical interactions, dissociations energies) -protein structure: primary, secondary, tertiary, quaternary structures. -protein folding problem Levinthal's paradox Anfinsen's dogma -relation between: prot. sequence, prot. structure and prot. function 6.- PDB (protein data bank) -intro to the data Bank. -evolution of the database -current state, diff. experimental method contributions -X-ray crystallography -nuclear magnetic resonance -electron microscopy -RCSB PDB, what can I retrieve from a PDB id? -PDB text file description -graphical tools for visualization: Chimera